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Search Results for " PDGF 2 "

ターゲット

阻害剤

天然化合物

304

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T0097L	Pazopanib	GW786034	VEGFR , FGFR , PDGFR , c-Kit , Autophagy
	Pazopanib (GW786034), a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result i...		VEGFR , FGFR , PDGFR , c-Kit , Autophagy
T15616	JNJ-10198409	JNJ-10198409	PDGFR
	JNJ- 10198409 is a relatively selective and ATP competitive PDGF-RTK inhibitor (IC50=2 nM). JNJ-10198409 has good activity against PDGFR-β kinase (IC50=4.2 nM) and PDGFR-α kinase (IC50=45 nM). It is a dual-mechanism, ant...		PDGFR
T4205	AG-494	Tyrphostin AG-494,AG 494,Tyrphostin B48	EGFR , CDK
	AG-494 (Tyrphostin B48) is an inhibitor of epidermal growth factor receptor kinase.		EGFR , CDK
T2160	Suramin Sodium Salt	BAY-205,Suramin hexasodium salt,NF-060	Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite
	Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f...
T71944	FGF/PDGF/VEGF RTK Inhibitor
	FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h...
T67442	CGP-53716
	The growth factors, platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) play major roles in enhanced smooth muscle cells growth in rodent blood vessels after vascular injury. Tyrosine kinase i...
T36547	Quazinone
	Quazinone is a selective inhibitor of phosphodiesterase 3 (PDE3) with positive inotropic and vasodilating properties.1,2 It induces relaxation of precontracted isolated human cavernous smooth muscle (IC50 = 4.2 μM).1 Qua...
T37079	VEGFR2 Kinase Inhibitor II
	Vascular endothelial growth factor receptor 2 (VEGFR2, also known as KDR and FLK1) is a receptor tyrosine kinase that regulates angiogenesis, vascular development, and embryonic hematopoiesis in response to VEGF isoforms...

Compounds

Pazopanib

T0097L

Synonym: GW786034

Target: VEGFR, FGFR, PDGFR, c-Kit, Autophagy

JNJ-10198409

T15616

Synonym: JNJ-10198409

Target: PDGFR

AG-494

T4205

Synonym: Tyrphostin AG-494,AG 494,Tyrphostin B48

Target: EGFR, CDK

Suramin Sodium Salt

T2160

Synonym: BAY-205,Suramin hexasodium salt,NF-060

Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite

FGF/PDGF/VEGF RTK Inhibitor

VEGFR2 Kinase Inhibitor II

T37079

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
TN2354	Methylnissolin	3-Hydroxy-9,10-dimethoxyptercarpan	ERK , PDGFR
	Methylnissolin (3-Hydroxy-9,10-dimethoxyptercarpan) is derived from Astragalus and has antibacterial and anti-cancer effects.		ERK , PDGFR
T6S0655	Corynoxeine		ERK
	1. Corynoxeine is a potent ERK1/2 inhibitor of key PDGF-BB-induced VSMC proliferation and may be useful in the prevention and treatment of vascular diseases and restenosis after angioplasty.		ERK
T5S1103	Isoliensinine	Isoliensinin	Apoptosis , Antioxidant
	1. Isoliensinine (Isoliensinin), a natural phenolic bisbenzyltetrahydroisoquinoline alkaloid, has received considerable attention for its potential biological effects such as antioxidant and anti-HIV activities. 2. Isoli...		Apoptosis , Antioxidant

天然物製品

Methylnissolin

TN2354

Synonym: 3-Hydroxy-9,10-dimethoxyptercarpan

Synonym: Isoliensinin

Target: Apoptosis, Antioxidant

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04644	PDGFB Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionalit...
TMPK-00481	PDGF R beta/CD140b Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Platelet-derived growth factor receptor (PDGFR) signaling is involved in proliferation and survival in a wide array of cell types.PDGFR-β signalling, via TGF-β signalling, may be crucial for restoration of BBB integrity ...
TMPK-00421	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPK-01050	PDGF R beta/CD140b Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	PDGF R beta/CD140b Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.25 kDa and the accession number is Q6QNF3.
TMPK-00422	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PDGF R beta/CD140b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59 kDa and the accession number is P09619.
TMPK-00419	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPK-00943	PDGF R alpha/PDGFRA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPK-00420	PDGF R alpha/PDGFRA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Platelet-derived growth factor is commonly known as a mitogen. Many research data suggest a role for PDGF-beta R in the mitogenic response of mesangial cells. There are four members of PDGF family known as PDGF-A chain, ...
TMPJ-01050	GRB2 Protein, Human, Recombinant (His)	Human	E. coli
	As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated E...
TMPY-02131	Acid Phosphatase/ACP1 Protein, Human, Recombinant (GST)	Human	E. coli
	The low molecular weight phosphotyrosine phosphatase (LMW-PTP), also known as Acid phosphatase 1 (ACP1), belongs to the low molecular weight phosphotyrosine protein phosphatase family are involved in the regulation of im...
TMPJ-01109	EIF4EBP2 Protein, Human, Recombinant (His)	Human	E. coli
	Eukaryotic Translation Initiation Factor 4E-Binding Protein 2 (EIF4EBP2) is a member of the Eukaryotic Translation Initiation Factor 4E Binding Protein Family. EIF4EBP2 regulates eIF4E activity by preventing its assembly...
TMPJ-00011	CXCL2 Protein, Mouse, Recombinant	Mouse	E. coli
	C-X-C motif chemokine 2 (CXCL2,MIP-2) belongs to the intercrine alpha (chemokine CxC) family. It was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin...
TMPJ-00054	PLGF-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. Alternate splicing results in at least three human mature PlGF f...
TMPY-04116	KRAS Protein,Human,Recombinant(G12C & Q61H, His)	Human	E. coli
	KRAS Protein,Human,Recombinant(G12C & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-01691	Clusterin Protein, Human, Recombinant (CLU34, His)	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-00871	LAYN Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	LAYN Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q6UX15-2.
TMPY-02011	CD96 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-05288	PLGF/PGF Protein, Human, Recombinant (aa 19-149)	Human	E. coli
	PLGF/PGF Protein, Human, Recombinant (aa 19-149) is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P49763-2.
TMPY-00005	FGF-8a Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-00849	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.72 kDa and the accession number is Q01638-2.
TMPY-00850	ST2/IL-1 RL1 Protein, Human, Recombinant	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.6 kDa and the accession number is Q01638-2.
TMPY-02792	GDNF Protein, Human, Recombinant (HEK293)	Human	HEK293 Cells
	GDNF Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.1 kDa and the accession number is P39905-2.
TMPY-02358	CD98 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	CD98 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P10852-2.
TMPY-00748	Nectin-2 Protein, Human, Recombinant	Human	HEK293 Cells
	Nectin-2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 36.2 kDa and the accession number is Q92692-2.
TMPY-00341	FGFR3 Protein, Human, Recombinant (alpha IIIb, His)	Human	HEK293 Cells
	FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-04396	C-ABL/ABL1 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cy...
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His)	Human	HEK293 Cells
	Neuropilin-1 Protein, Human, Recombinant (isoform b, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 71.3 kDa and the accession number is O14786-2.
TMPY-01199	CD74 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	CD74 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.4 kDa and the accession number is P04233-2.
TMPY-04113	KRAS Protein,Human,Recombinant(G12D & Q61H, His)	Human	E. coli
	KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	SDF-1 Protein, Human, Recombinant (isoform a) is expressed in E. coli expression system. The predicted molecular weight is 8 kDa and the accession number is P48061-2.
TMPY-05586	CD28H/TMIGD2 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	The orthologue of human IGPR-1 is found only in eukaryotes, including primates, the guinea pig, canines, felines, dolphins, bovines, the llama, bats, the common shrew, and horses. Of interest, the IGPR-1 gene is absent i...
TMPY-05427	CD19 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CD19 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is P15391-2.
TMPY-01359	ST2/IL-1 RL1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	ST2/IL-1 RL1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.5 kDa and the accession number is Q01638-2.
TMPY-00751	TrkB Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293 Cells
	G-CSF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.7 kDa and the accession number is P09919-2.
TMPY-02096	TACI Protein, Human, Recombinant (His)	Human	HEK293 Cells
	TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-04844	BTN3A1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	BTN3A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is O00481-2.
TMPY-01935	C-Kit Protein, Human, Recombinant (His)	Human	HEK293 Cells
	c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.7 kDa and the accession number is P10721-2.
TMPY-01985	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	CD32B/Fcgr2b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 24 kDa and the accession number is P31994-2.
TMPY-04356	GSK3B Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPJ-00850	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)	Mouse	HEK293 Cells
	ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-00127	M-CSF/CSF1 Protein, Human, Recombinant	Human	HEK293 Cells
	M-CSF/CSF1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 18.4 kDa and the accession number is P09603-2.
TMPY-01871	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His)	Human	HEK293 Cells
	IL-5R alpha/CD125 Protein, Human, Recombinant(aa 1-335, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is Q01344-2.
TMPY-02231	TrkB Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-02432	VEGF164 Protein, Rat, Recombinant	Rat	Baculovirus Insect Cells
	VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-03425	Tau Protein, Human, Recombinant (His)	Human	E. coli
	MAPT (microtubule-associated protein tau) can produce tau proteins. Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are...
TMPY-01888	KRAS Protein,Human, Recombinant (Q61H, His)	Human	E. coli
	KRAS Protein,Human, Recombinant (Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 22.5 kDa and the accession number is P01116-2.
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